PAEDIATRICS Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies
نویسندگان
چکیده
Methods. A comprehensive literature search was conducted to identify clinical trials that focused on the prevention of EA in children anaesthetized with sevoflurane, desflurane, or both. The data from each trial were combined using the Mantel–Haenszel model to calculate the pooled odds ratio (OR) and 95% confidence interval. I statistics were used to assess statistics heterogeneity and the funnel plot and the Begg–Mazumdar test to assess bias.
منابع مشابه
Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies.
BACKGROUND Emergence agitation (EA) in children is increased after sevoflurane anaesthesia. The efficacy of prophylactic treatment is controversial. The aim of this study was to provide a meta-analysis of the studies of the pharmacological prevention of EA in children. METHODS A comprehensive literature search was conducted to identify clinical trials that focused on the prevention of EA in c...
متن کامل'From darkness into light': time to make awake intubation with videolaryngoscopy the primary technique for an anticipated difficult airway?
Effect of ketamine versus alfentanil following midazolam in preventing emergence agitation in children after sevoflurane anaesthesia: A prospective random-ized clinical trial. Ketamine is effective in decreasing the incidence of emergence agitation in children undergoing dental repair under sevo-flurane general anesthesia. Effects of ketamine and midazolam on emergence agitation after sevoflura...
متن کاملEmergence Delirium
Emergence delirium (ED) also referred to as emergence agitation (EA) is a well documented phenomenon occurring in children and adults in the immediate postoperative period. With the recent popularity of the newer inhalation agents desflurane and sevoflurane, numerous clinical studies have been published questioning the association of these anesthetics with an increased incidence of emergence de...
متن کاملComparison of the incidence of emergence agitation and emergence times between desflurane and sevoflurane anesthesia in children
BACKGROUND The differences in the incidence and severity of emergence agitation (EA) and emergence times between desflurane and sevoflurane anesthesia have not been as clearly elucidated in children as in adults. METHODS The design of the study is a systematic review with meta-analysis of randomized controlled trials. The study methodology is based on the Cochrane Review Methods. A comprehens...
متن کاملThe effect of fentanyl on the emergence characteristics after desflurane or sevoflurane anesthesia in children.
UNLABELLED Desflurane and sevoflurane anesthesia are associated with emergence agitation in children. In this study, we examined the effect of a single intraoperative dose of fentanyl on emergence characteristics in children undergoing adenoidectomy. One hundred children, 2-7 yr old, were randomly assigned to receive desflurane or sevoflurane for maintenance of general anesthesia after an inhal...
متن کامل